If the crew are lucky, the ship will simply be returned to normal space, or be destroyed instantly and relatively painlessly. Should something go wrong during hyperspace travel, results vary. Clearly marked paths may be slightly safer, or ships may generate a safe field around themselves while travelling. It's sure to be mind-bendingly different and hostile to conventional life � even more so than the void of space itself. Hyperspace, being Another Dimension or close, sets aside the natural laws that our universe and biologies need. Anything with the power to thrust people across light-years rightly should scare their astropants off. And let's not even get started on the whole 'infinite void of nothingness between the stars' aspect.
Heinlein's The Moon Is a Harsh Mistress and Larry Niven's short stories have pointed out that, barring Faster-Than-Light Travel, convenient real-space travel between planets has energy requirements on the same order as making significant holes in them. Contemporary space shuttles ride pillars of fire and launching one involves spraying 1100 cubic meters of water on the pad as a muffler to keep the craft from being damaged by the noise. There are very few things about space that are not freaky.
